INFLUENCE OF NITROGEN-BALANCE AND INTESTINAL GLUCOSE-ABSORPTION ON GROWTH OF RATS RECOVERY FROM EARLY UNDERNUTRITION

被引:4
作者
GUTIERREZ, JM [1 ]
ALVAREZ, I [1 ]
DIAZ, F [1 ]
FERNANDEZ, S [1 ]
MENENDEZPATTERSON, A [1 ]
机构
[1] UNIV OVIEDO,DEPT BIOL FUNC FISIOL,E-33006 OVIEDO,SPAIN
关键词
EARLY MALNUTRITION; GROWTH; NITROGEN BALANCE; INTESTINAL GLUCOSE ABSORPTION;
D O I
10.1016/S0271-5317(05)80475-0
中图分类号
R15 [营养卫生、食品卫生]; TS201 [基础科学];
学科分类号
100403 ;
摘要
The present work analyses the role of food and water intake, nitrogen balance, "in vivo" D-glucose intestinal absorption and plasma insulin level in body weight gain by early malnourished male rats after two or four months of rehabilitation with normal diet. Malnutrition was applied "in uterus" and during the lactation period by reducing normal diet. At 3 and 5 months of age, the animals remained in metabolic cages during ten days, were then anaesthetized, and the plasma insulin level and "in vivo" D-glucose intestinal absorption were measured. Comparison of the ratio of weight gained to the amount of food consumed demonstrates a greater food efficiency in the malnourished animals at 3 months of age, which is explained by the increased nitrogen balance measured by 100 g of body weight. The evolution of body weight gain in the control and malnourished animals was similar at 5 months of age. If we compare the results at 3 and 5 months of age, the data suggests that early malnutrition can act by retarding age-associated physiological changes such as intestinal and pancreatic processes.
引用
收藏
页码:1427 / 1437
页数:11
相关论文
共 23 条
[1]  
ALVAREZORDAS I, 1991, ANN NUTR METAB
[2]   EFFECT OF THE DURATION OF MALNUTRITION AND OF NUTRITIONAL REHABILITATION ON BLOOD-GLUCOSE HOMEOSTASIS AND PANCREATIC HORMONES IN RATS [J].
DOLLET, JM ;
BECK, B ;
MAX, JP .
BRITISH JOURNAL OF NUTRITION, 1988, 60 (01) :69-76
[3]   MALNUTRITION INUTERO AND DURING LACTATION IN THE RAT - RELATIONSHIP OF DAMS WEIGHT-GAIN AND DEVELOPMENT OF SUCKLING [J].
FERNANDEZ, SF ;
MENENDEZ, MF ;
FERNANDEZ, BM ;
PATTERSON, AM .
NUTRITION RESEARCH, 1985, 5 (04) :413-421
[4]   INFLUENCE OF MALNUTRITION DURING GESTATION AND SUCKLING ON REPRODUCTIVE FUNCTION AND SEXUAL-BEHAVIOR IN RATS [J].
FERNANDEZ, SF ;
ORDAS, IA ;
SANCHEZ, JMG ;
MARIN, B ;
MENENDEZPATTERSON, A .
NUTRITION RESEARCH, 1986, 6 (05) :517-526
[5]  
FISHER RA, 1957, STATISTICAL TABLES B
[6]  
GUTIERREZ JM, 1988, REV ESP FISIOL, V44, P413
[7]   CHANGES IN ADIPOSE-TISSUE OF THE RAT DUE TO EARLY UNDERNUTRITION FOLLOWED BY REHABILITATION .1. BODY-COMPOSITION AND ADIPOSE-TISSUE CELLULARITY [J].
HARRIS, PM .
BRITISH JOURNAL OF NUTRITION, 1980, 43 (01) :15-26
[8]   EFFECT OF EARLY POSTNATAL ACQUIRED MALNUTRITION ON INTESTINAL GROWTH, DISACCHARIDASES AND ENTEROKINASE [J].
HATCH, TF ;
LEBENTHAL, E ;
BRANSKI, D ;
KRASNER, J .
JOURNAL OF NUTRITION, 1979, 109 (11) :1874-1879
[9]  
HUGHES PCR, 1986, ACTA ANAT, V125, P50
[10]  
LOWRY OH, 1951, J BIOL CHEM, V193, P265