BROMINATED INDOLE ALKALOIDS FROM THE MARINE TUNICATE PSEUDODISTOMA-ARBORESCENS

被引：63

作者：

CHBANI, M

PAIS, M

DELAUNEUX, JM

DEBITUS, C

机构：

[1] CNRS,INST CHIM SUBST NAT,F-91198 GIF SUR YVETTE,FRANCE

[2] ORSTOM,NOUMEA,NEW CALEDONIA

来源：

JOURNAL OF NATURAL PRODUCTS | 1993年 / 56卷 / 01期

关键词：

D O I：

10.1021/np50091a014

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Chemical investigation of the cytotoxic CH2Cl2-soluble extract of the marine tunicate Pseudodistoma arborescens led to the isolation of four brominated indole alkaloids, arborescidines A [1], B [2], C (3), and D [4], which were characterized by their spectral data, especially 2D nmr. Only arborescidine D [4] showed moderate activity (IC50 3 mug/ml) in vitro against the growth of KB human buccal carbinoma cells.

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页码：99 / 104

页数：6

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