GENETIC-ANALYSIS OF A CHINESE-HAMSTER CELL LINE LACKING A G1-PHASE

被引：24

作者：

LISKAY, RM

机构：

[1] Department of Molecular, Cellular and Developmental Biology, University of Colorado, Boulder

来源：

EXPERIMENTAL CELL RESEARCH | 1978年 / 114卷 / 01期

基金：

美国国家卫生研究院;

关键词：

D O I：

10.1016/0014-4827(78)90037-X

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

A Chinese hamster cell line (V79-8), which lacks a measurable G1 phase in its cell cycle (G1-), has been investigated utilizing somatic cell hybrids. The results indicate that the G1- phenotype is dominant in two types of intraspecific hybrids and, surprisingly is in contrast recessive in two different interspecific crosses. Furthermore, the G1- V79-8 cell line complements two different G1 defective cell cycle mutants, suggesting that V79-8 retains and can express at least some G1-specific functions. © 1978.

引用

页码：69 / 77

页数：9

共 30 条

[1] DNA SYNTHETIC RATE AND DNA CONTENT OF NUCLEATED ERYTHROID CELLS
ALPEN, EL
JOHNSTON, ME
[J]. EXPERIMENTAL CELL RESEARCH, 1967, 47 (1-2) : 177 - &
[2] TEMPERATURE-SENSITIVE CELL-CYCLE MUTANT OF BHK CELL LINE
BURSTIN, SJ
MEISS, HK
BASILICO, C
[J]. JOURNAL OF CELLULAR PHYSIOLOGY, 1974, 84 (03) : 397 - 408
[3] CHU EHY, 1970, MAMMALIAN CHROMOSOME, V11, P58
[4] CELL-CYCLE, CELL-SHAPE MUTANT WITH FEATURES OF G-0 STATE
CRANE, MSJ
THOMAS, DB
[J]. NATURE, 1976, 261 (5557) : 205 - 208
[5] KARYOTYPIC ANALYSIS OF A NEAR-DIPLOID ESTABLISHED MOUSE CELL LINE
FARBER, RA
LISKAY, RM
[J]. CYTOGENETICS AND CELL GENETICS, 1974, 13 (04): : 384 - 396
[6] FORD DK, 1958, J NATL CANCER I, V21, P393
[7] CELL LIFE CYCLE DURING EARLY EMBRYOGENESIS OF MOUSE
GAMOW, EI
PRESCOTT, DM
[J]. EXPERIMENTAL CELL RESEARCH, 1970, 59 (01) : 117 - &
[8] GRAVES JAM, 1972, EXP CELL RES, V73, P81
[9] GENETIC-CONTROL OF CELL-DIVISION CYCLE IN YEAST
HARTWELL, LH
CULOTTI, J
PRINGLE, JR
REID, BJ
[J]. SCIENCE, 1974, 183 (4120) : 46 - 51
[10] TEMPERATURE-SENSITIVE CELL-CYCLE MUTANTS - CHINESE-HAMSTER CELL LINE WITH A REVERSIBLE BLOCK IN CYTOKINESIS
HATZFELD, J
BUTTIN, G
[J]. CELL, 1975, 5 (02) : 123 - 129

← 1 2 3 →