EFFECT OF TRISODIUM PHOSPHONOFORMATE IN GENITAL-INFECTION OF FEMALE GUINEA-PIGS WITH HERPES-SIMPLEX VIRUS TYPE-2

被引：34

作者：

ALENIUS, S

NORDLINDER, H

机构：

[1] NATL VET INST,CTR BIOMED,S-75123 UPPSALA,SWEDEN

[2] UNIV UPPSALA,FAC MED,DEPT PATHOL,S-75105 UPPSALA,SWEDEN

来源：

ARCHIVES OF VIROLOGY | 1979年 / 60卷 / 3-4期

关键词：

D O I：

10.1007/BF01317491

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

A genital herpesvirus type 2 infection in guinea pigs has been used to evaluate the inhibitory effect of phosphonoformate on the infection. An early topical treatment prevented the appearance of vesicles and histopathological changes and no virus could be recovered. When treatment, either topical or both systemic and topical, was delayed to 24 hours post infection no therapeutic effect was observed. © 1979 Springer-Verlag.

引用

页码：197 / 206

页数：10

共 26 条

[1]

ADAMS HG, 1976, ANTIVIRALS CLIN POTE, P151

[2] THERAPEUTIC EFFECT OF TRISODIUM PHOSPHONOFORMATE ON CUTANEOUS HERPESVIRUS INFECTION IN GUINEA-PIGS [J].