CAPSIMYCIN, A NEW ANTIBIOTIC .1. PRODUCTION, ISOLATION AND PROPERTIES

被引：28

作者：

AIZAWA, S

AKUTSU, H

SATOMI, T

NAGATSU, T

TAGUCHI, R

SEINO, A

机构：

[1] Central Research Laboratories, Kaken Chemical Co., Ltd., Bunkyo-ku, Tokyo

来源：

JOURNAL OF ANTIBIOTICS | 1979年 / 32卷 / 03期

关键词：

D O I：

10.7164/antibiotics.32.193

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Capsimycin is a new antifungal antibiotic produced by a strain of Streptomyces sp. C 49-87. The active substance in the fermented broth was isolated by solvent extraction followed by silica gel column chromatography. The antibiotic melts at 186°C (decomp.) and has a molecular formula C30H40N2O6. It exhibits marked inhibitory activity against Phytophthora capsici (Leaf blight disease of cucumber) and Pythium debaryanum (Dampingoff disease of cucumber). © 1979, JAPAN ANTIBIOTICS RESEARCH ASSOCIATION. All rights reserved.

引用

页码：193 / 196

页数：4

共 9 条

[1]

Burmeister HR, 1976, U. S. Patent, Patent No. [3,959,468, 3959468, 3,959,468 A.]

[2] METHYMYCIN - REDUCTION AND OXIDATION STUDIES [J].

DJERASSI, C ;

BOWERS, A ;

KHASTGIR, HN .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1956, 78 (08) :1729-1732

[3]

HARADA J, 1958, J ANTIBIOTICS A, V11, P32

[4] NEW ANTIBIOTIC, IKARUGAMYCIN [J].

JOMON, K ;

AJISAKA, M ;

SAKAI, H ;

KURODA, Y .

JOURNAL OF ANTIBIOTICS, 1972, 25 (05) :271-&

[5] TIRANDAMYCIN, A NEW ANTIBIOTIC ISOLATION AND CHARACTERIZATION [J].

MEYER, CE .

JOURNAL OF ANTIBIOTICS, 1971, 24 (08) :558-&

[6] STREPTOLYDIGIN .1. STREPTOLIC ACID [J].

RINEHART, KL ;

SPICER, LD ;

EPSTEIN, WW ;

BECK, JR .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1963, 85 (24) :4035-&

[7]

UMEZAWA H, 1967, INDEX ANTIBIOTICS AC, P688

[8]

WATANABE K, 1957, J ANTIBIOT, V10, P39

[9]

YAMAGUCHI H, 1957, J ANTIBIOT, V10, P195

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