KINETIC RESOLUTION OF N-PROTECTED AMINO-ACID ESTERS IN ORGANIC-SOLVENTS CATALYZED BY A STABLE INDUSTRIAL ALKALINE PROTEASE

被引：33

作者：

CHEN, ST

CHEN, SY

HSIAO, SC

WANG, KT

机构：

[1] Institute of Biological Chemistry, Academia Sinica, Taipei, 10098

来源：

BIOTECHNOLOGY LETTERS | 1991年 / 13卷 / 11期

关键词：

D O I：

10.1007/BF01026757

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

An industrial alkaline protease "Alcalase" has been found to be very stable in organic solvents and usable as a catalyst for resolution of N-protected amino acids, in both aqueous solution and organic solvent with high yield and optical purity. Only the L-amino acid ester has been hydrolysed.

引用

页码：773 / 778

页数：6

共 9 条

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