YEAST EICOSANOIDS .3. THE DISTRIBUTION OF ARACHIDONIC-ACID METABOLITES IN THE LIFE-CYCLE OF DIPODASCOPSIS-UNINUCLEATA

被引：13

作者：

COETZEE, DJ

KOCK, JLF

BOTHA, A

VANDYK, MS

SMIT, EJ

BOTES, PJ

AUGUSTYN, OPH

机构：

[1] UNIV ORANGE FREE STATE,DEPT MICROBIOL & BIOCHEM,POB 339,BLOEMFONTEIN 9300,SOUTH AFRICA

[2] VITICULTURAL & OENOL INST,STELLENBOSCH 7600,SOUTH AFRICA

来源：

SYSTEMATIC AND APPLIED MICROBIOLOGY | 1992年 / 15卷 / 02期

关键词：

DIPODASCOPSIS-UNINUCLEATA; PROSTAGLANDINS; LIPOXYGENASE PRODUCTS; NSAID; LIFE CYCLE; ASPIRIN SENSITIVITY;

D O I：

10.1016/S0723-2020(11)80105-0

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

In this study, arachidonic acid metabolites have been implicated in the life cycle of Dipodascopsis uninucleata, especially during ascospore development. We have found that aspirin (I mM) in the culture media inhibit the production of prostaglandins and 3-HETE while the levels of lipoxygenase products increased significantly. It was also found that most arachidonic acid metabolites are associated with ascospores and corresponding supernatant. A down regulation in labelled arachidonic acid metabolites occurs during the life cycle in both vegetative cells and supernatants as the asexual phase progresses towards the sexual phase.

引用

页码：311 / 318

页数：8