CYTOGENETIC CHARACTERIZATION OF A NEW HUMAN PAPILLARY THYROID-CARCINOMA PERMANENT CELL-LINE (GLAG-66)

被引：15

作者：

ANTONINI, P

LINARES, G

GAILLARD, N

VENUAT, AM

SCHLUMBERGER, M

TRAVAGLI, JP

CAILLOU, B

BERGER, R

PARMENTIER, C

机构：

[1] INST GUSTAVE ROUSSY,DEPT CHIRURG,F-94805 VILLEJUIF,FRANCE

[2] INST GUSTAVE ROUSSY,ANAT PATHOL LAB,F-94805 VILLEJUIF,FRANCE

[3] HOP ST LOUIS,INSERM,U301,F-75010 PARIS,FRANCE

来源：

CANCER GENETICS AND CYTOGENETICS | 1993年 / 67卷 / 02期

关键词：

D O I：

10.1016/0165-4608(93)90163-G

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

A new permanent cell line (GLAG-66) has been established from the metastases of a papillary thyroid carcinoma in a male patient. Herein are reported the cytogenetic characteristics of this new cell line, which is tumorigenic in athymic mice. An aneuploid chromosomal pattern was observed (48 chromosomes) with various chromosomal abnormalities. The karyotype was: 48,XY,der(1)t(9;1;9), +der(8)t(1;8),der(9)t(1;9),der(9)t(1;9), +14. This cell line should prove to be of great value in the study of the biology of human papillary thyroid carcinomas.

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页码：117 / 122

页数：6

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