NOVEL NEMATOCIDAL AGENTS FROM CURCUMA-COMOSA

被引：50

作者：

JURGENS, TM

FRAZIER, EG

SCHAEFFER, JM

JONES, TE

ZINK, DL

BORRIS, RP

NANAKORN, W

BECK, HT

BALICK, MJ

机构：

[1] MERCK & CO INC, RES LABS, RAHWAY, NJ 07065 USA

[2] ROYAL FOREST DEPT, FOREST HERBARIUM, BANGKOK 10900, THAILAND

[3] NEW YORK BOT GARDEN, INST ECON BOT, BRONX, NY 10458 USA

来源：

JOURNAL OF NATURAL PRODUCTS | 1994年 / 57卷 / 02期

关键词：

D O I：

10.1021/np50104a006

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Cuvcuma comosa is a member of the economically important plane family, Zingiberaceae. A methanolic extract of C. comosa was shown to be nematocidal when tested against the free-living nematode Caenorhabditis elegans. Five diphenylheptanoids [1-5], one new and four known, have been isolated and shown to be responsible for the activity. This is the first report of three of these compounds [1, 2, 4] being isolated from a natural source.

引用

页码：230 / 235

页数：6

共 26 条

[1] CURCUMIN - A POTENT INHIBITOR OF LEUKOTRIENE-B4 FORMATION IN RAT PERITONEAL POLYMORPHONUCLEAR NEUTROPHILS (PMNL) [J].