THE SYNTHESIS OF (6R)-[6-H-2]-5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE AND (6S)-[6-H-2]-5-ENOLPYRUVYLSHIKIMATE-3-PHOSPHATE

被引：8

作者：

BALASUBRAMANIAN, S ^{[1
]}

ABELL, C ^{[1
]}

机构：

[1] UNIV CAMBRIDGE,CHEM LAB,LENSFIELD RD,CAMBRIDGE CB2 1EW,ENGLAND

来源：

TETRAHEDRON LETTERS | 1991年 / 32卷 / 07期

关键词：

D O I：

10.1016/S0040-4039(00)92131-2

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

(6R)-[6-2H]- and (6S)-[6-2H]5-enolpyruvylshikimate-3-phosphate have been synthesised for the kinetic analysis of the chorismate synthase reaction. The synthesis uses purified shikimate kinase and EPSP synthase for enantiospecific biotransformations and also clarifies the stereochemical course of the Diels Alder reaction in the synthesis of shikimic acid.

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页码：963 / 966

页数：4

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