SELECTIVE LITHIATION OF BIS(AZOL-1-YL)METHANES

被引：47

作者：

DIEZBARRA, E

DELAHOZ, A

SANCHEZMIGALLON, A

TEJEDA, J

机构：

[1] Facultad de Química, Universidad de Castilla-La Mancha

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1993年 / 09期

关键词：

D O I：

10.1039/p19930001079

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Lithiation of bis(azol-1-yl)methanes and subsequent reaction with electrophiles yields selectively mono- and di-ring-substituted derivatives. The regioselectivity observed is explained in terms of the structure of the substrate, the hard and soft acids and bases principle, and the nature of the electrophile used.

引用

页码：1079 / 1083

页数：5

共 7 条

[1] TRIAZOLE PHOSPHONATES - ELECTROPHILIC SUBSTITUTION OF 1-SUBSTITUTED-1H-1,2,4-TRIAZOLES VIA LITHIATED TRIAZOLE INTERMEDIATES [J].