REAPPRAISAL OF THE INCIDENCE RATE OF DUCHENNE AND BECKER MUSCULAR-DYSTROPHIES ON THE BASIS OF MOLECULAR DIAGNOSIS

被引：19

作者：

MOSTACCIUOLO, ML ^{[1
]}

MIORIN, M ^{[1
]}

PEGORARO, E ^{[1
]}

FANIN, M ^{[1
]}

SCHIAVON, F ^{[1
]}

VITIELLO, L ^{[1
]}

SAAD, FA ^{[1
]}

ANGELINI, C ^{[1
]}

DANIELI, GA ^{[1
]}

机构：

[1] UNIV PADUA, DEPT NEUROL, PADUA, ITALY

来源：

NEUROEPIDEMIOLOGY | 1993年 / 12卷 / 06期

关键词：

DUCHENNE DYSTROPHY; BECKER DYSTROPHY; DYSTROPHIN; EPIDEMIOLOGY;

D O I：

10.1159/000110334

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

The incidence rates of Duchenne and Becker muscular dystrophies (X-linked recessive) in a given sample of the Italian population were recalculated using the results of DNA and dystrophin analysis. While the incidence rate of Duchenne muscular dystrophy remained unchanged, the new figure for the incidence of Becker muscular dystrophy (7.2 per 100,000 male live births) was much higher than previously reported, since molecular diagnosis revealed additional cryptic cases, but this incidence is still an underestimate.

引用

页码：326 / 330

页数：5

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