CA 19-9 AS A PROGNOSTIC INDEX AFTER RESECTION FOR PANCREATIC-CANCER

被引：58

作者：

SPERTI, C ^{[1
]}

PASQUALI, C ^{[1
]}

CATALINI, S ^{[1
]}

CAPPELLAZZO, F ^{[1
]}

BONADIMANI, B ^{[1
]}

BEHBOO, R ^{[1
]}

PEDRAZZOLI, S ^{[1
]}

机构：

[1] UNIV PADUA, DEPT SURG, VIA FACCIOLATI 71, I-35127 PADUA, ITALY

来源：

JOURNAL OF SURGICAL ONCOLOGY | 1993年 / 52卷 / 03期

关键词：

TUMOR MARKERS; CARBOHYDRATE ANTIGEN; FOLLOW-UP; PANCREATIC NEOPLASMS; PANCREATECTOMY;

D O I：

10.1002/jso.2930520302

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Serial serum CA 19-9 assays were performed in 30 consecutive patients who underwent resection for pancreatic cancer. Patients with preoperative CA 19-9 levels < 200 U/ml had significantly better prognosis than those with CA 19-9 > 200 U/ml (P < 0.001). Serum tumor marker normalized in 14 patients after tumor resection, and survival in this group was significantly higher than that of patients with persistently elevated CA 19-9 (P < 0.0001). Prognosis was also influenced by absence of lymph node metastases (P < 0.02) and radicality of resection (P < 0.005). Elevation of serum CA 19-9 levels after operation well predicted tumor recurrence from 1-10 months before clinical and radiological evidence. CA 19-9 determination is useful as a prognostic index after resection for pancreatic carcinoma and as a surveillance test in monitoring the efficacy of treatment.

引用

页码：137 / 141

页数：5

共 29 条

[1] ELEVATED SERUM LEVELS OF TUMOR-MARKER CA19-9 IN ACUTE CHOLANGITIS [J].