CORRECTION OF THE QT INTERVAL IN CHILDREN

被引:6
作者
AIHOSHI, S [1 ]
YOSHINAGA, M [1 ]
TOMARI, T [1 ]
NAKAMURA, M [1 ]
NOMURA, Y [1 ]
OKU, S [1 ]
HARAGUCHI, T [1 ]
OSAWA, N [1 ]
MIYATA, K [1 ]
机构
[1] KAGOSHIMA UNIV, FAC MED, DEPT PUBL HLTH, KAGOSHIMA 890, JAPAN
来源
JAPANESE CIRCULATION JOURNAL-ENGLISH EDITION | 1995年 / 59卷 / 04期
关键词
LONG QT SYNDROME; EXPONENTIAL FORMULA; FRIDERICIAS FORMULA; MEAN-SQUARED RESIDUAL VALUES; AKAIKE INFORMATION CRITERION;
D O I
10.1253/jcj.59.190
中图分类号
N09 [自然科学史]; B [哲学、宗教];
学科分类号
01 ; 0101 ; 010108 ; 060207 ; 060305 ; 0712 ;
摘要
We evaluated the usefulness of 11 formulas for correcting the QT interval in children, including the square root, cubic root, logarithmic, linear, exponential, and inverse formulas using the Mean-squared residual (MSR) values and Akaike Information Criterion (AIC) in 8,086 first-graders, 9,989 seventh-graders, and 5,786 tenth-graders. The subjects were divided into six groups according to age and sex. MSR and AIC values were lowest in all of the groups for the exponential formula (eQTc) and Fridericia's formula (fQTc). We then evaluated the relative usefulness of these two formulas by determining the optimal value for parameter k using the following exponential model: eQTc=(QT interval)/(RR interval)(k). The best-fit value for k was different for each group. However, the tentative abnormal eQTc and fQTc values, determined by statistical analysis, were equivalent in all groups when 0.31 was used as the exponential parameter k. These results suggest that the exponential formula and Fridericia's formula are equally useful for screening for QT prolongation.
引用
收藏
页码:190 / 197
页数:8
相关论文
共 25 条
[1]  
Bazett H.C., An analysis of the time-relations of the electrocardiogram, Heart, 7, pp. 353-370, (1920)
[2]  
Taggart P., Donaldson R., Green J., Joseph S.P., Kelly H.B., Marcomichelakis J., Noble D., White J., Interrelation of heart rate and autonomic activity in asymptomatic men with unobstructed coronary arteries, Br Heart J, 47, pp. 19-25, (1982)
[3]  
Ahnve S., Vallin H., Influence of heart rate and inhibition of antomatic tone on the QT interval, Circulation, 65, pp. 435-439, (1982)
[4]  
Maine J.R., Wrad D.E., Spurrell R.A.J., Camm A.J., The ventricular paced QT interval - The effect of rate and exercise, PACE, 5, pp. 352-358, (1982)
[5]  
Fridericia L.S., Die Systolendauer im Elektrokar-diogramm bei normalen Menschen und bei Herz-kranken, Acta Med Scand, 53, pp. 469-486, (1920)
[6]  
Ashman R., Normal duration of QT interval, Am Heart J, 23, pp. 522-534, (1920)
[7]  
Adams W., The normal duration of the electrocardiographic ventricular complex, J Clin Invest, 15, pp. 335-342, (1936)
[8]  
Kovacs S.J., The duration of the QT interval as a function of heart rate: A derivation based on physical principles and a comparison to measured values, Am Heart J, 110, pp. 872-878, (1985)
[9]  
Sarma J.S.M., Sarnia R.J., Bilitch M., Katz D., Song S.L., An exponential formula for heart rate dependence of QT interval during exercise and cardiac pacing in humans: Reevaluation of Bazett's formula, Am J Cardiol, 54, pp. 103-108, (1984)
[10]  
Sagie A., Larson M.G., Goldberg R.J., Bengtson J.R., Levy D., An improved method for adjusting the QT interval for heart rate (the Framingham Heart study), Am J Cardiol, 70, pp. 797-801, (1992)