FREE-RADICALS IMAGED INVIVO IN THE RAT BY USING PROTON ELECTRON DOUBLE-RESONANCE IMAGING

被引：42

作者：

LURIE, DJ

NICHOLSON, I

FOSTER, MA

MALLARD, JR

机构：

来源：

PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY OF LONDON SERIES A-MATHEMATICAL PHYSICAL AND ENGINEERING SCIENCES | 1990年 / 333卷 / 1632期

关键词：

D O I：

10.1098/rsta.1990.0172

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

A new technique called proton-electron double-resonance imaging is described for imaging free radicals in aqueous samples. The method is a combination of proton NMR imaging with nuclear electron double resonance. The results of using this technique to image free radicals in vivo in the rat are presented. Rats were injected intravenously with a nitroxide free radical solution and a series of images was obtained from which the clearance of the free radical through the liver and kidneys could be observed.

引用

页码：453 / 456

页数：4