MR IMAGING OF CORONARY-ARTERY FLOW IN ISOLATED AND INVIVO HEARTS

被引：40

作者：

BURSTEIN, D

机构：

[1] Department of Radiology, Charles A. Dana Research Institute, Beth Israel Hospital and Harvard Medical School, Boston, Massachusetts, 02215

来源：

JMRI-JOURNAL OF MAGNETIC RESONANCE IMAGING | 1991年 / 1卷 / 03期

关键词：

CORONARY VESSELS; MR STUDIES; 54.1214; FLOW DYNAMICS; 54.91; PULSE SEQUENCES; RAPID IMAGING; VASCULAR STUDIES;

D O I：

10.1002/jmri.1880010312

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

Methods for imaging flow in coronary arteries with magnetic resonance (MR) imaging techniques are demonstrated in isolated heart preparations and live animal models. Coronary artery flow was first imaged with a flow-compensated gradient-echo pulse sequence in isovolumic and working perfused rat hearts and then in vivo. A bolus tracking technique was used to measure flow velocity in the coronary arteries. Ultrafast gradient-echo imaging techniques were then applied, with high resolution obtained by combining the information from several cardiac cycles. A stimulated-echo pulse sequence was demonstrated as a method for performing coronary angiography by flow tagging in isovolumic perfused hearts. This report describes the results of coronary flow MR imaging in isolated rat hearts and live mice and rate. The general approach has proved useful in evaluating new methods for coronary MR angiography and should permit well-controlled studies of pathologic conditions. This ability to image coronary flow in isolated hearts and in small animals should permit integrated MR studies of coronary flow, myocardial perfusion, myocardial metabolism, and cellular ionic status.

引用

页码：337 / 346

页数：10

共 34 条

[1] Alfidi RJ, Masaryk TJ, Haacke EM, Et al., MR angiography of peripheral, carotid, and coronary arteries, AJR, 149, pp. 1097-1109, (1989)
[2] Edelman RR, Wentz KU, Mattle H, Et al., Projection arteriography and venography: initial clinical results with MR, Radiology, 172, pp. 351-357, (1989)
[3] Spritzer CE, Blinder RA, Vascular applications of magnetic resonance imaging, Magn Reson Q, 5, pp. 205-227, (1989)
[4] Paulin S, von Schulthess GK, Fossel E, Krayenbuehl HP, MR imaging of the aortic root and proximal coronary arteries, AJR, 148, pp. 665-670, (1987)
[5] Stehling M, Chapman B, Glover P, Et al., Real‐time NMR imaging of coronary vessels, Lancet, 2, pp. 964-965, (1987)
[6] Bisset GS, Strife JL, McCloskey J, MR imaging of coronary artery aneurysms in a child with Kawasaki disease, AJR, 152, pp. 805-807, (1989)
[7] Gomes AS, Lois JF, Drinkwater DC, Corday SR, Coronary artery bypass grafts: visualization with MR imaging, Radiology, 162, pp. 175-179, (1987)
[8] White RD, Caputo GR, Mark AS, Modin GW, Higgins CB, Coronary artery bypass graft patency: noninvasive evaluation with MR imaging, Radiology, 164, pp. 681-686, (1987)
[9] White RD, Pflugfelder PW, Lipton MJ, Higgins CB, Coronary artery bypass grafts: evaluation of patency with cine MR imaging, AJR, 150, pp. 1271-1274, (1988)
[10] Aurigemma GP, Reichek N, Axel L, Schiebler M, Harris C, Kressel HY, Noninvasive determination of coronary artery bypass graft patency by cine magnetic resonance imaging, Circulation, 80, pp. 1595-1602, (1989)

← 1 2 3 4 →