ANTI-TUMOR-PROMOTING ACTIVITIES OF AFROMOSIN AND SOYASAPONIN-I ISOLATED FROM WISTARIA-BRACHYBOTRYS

被引：55

作者：

KONOSHIMA, T ^{[1
]}

KOKUMAI, M ^{[1
]}

KOZUKA, M ^{[1
]}

TOKUDA, H ^{[1
]}

NISHINO, H ^{[1
]}

IWASHIMA, A ^{[1
]}

机构：

[1] KYOTO PREFECTURAL UNIV MED,DEPT BIOCHEM,KAMIKYO KU,KYOTO 602,JAPAN

来源：

JOURNAL OF NATURAL PRODUCTS | 1992年 / 55卷 / 12期

关键词：

D O I：

10.1021/np50090a011

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Afromosin [1] and soyasaponin I [2] isolated from Wistaria brachybotrys exhibited remarkable inhibitory effects on mouse skin tumor promotion, and afromosin also exhibited a significant inhibitory effect on pulmonary tumor promotion. The combined effects of these compounds on the two-stage skin carcinogenesis were also examined, and it was concluded that the combination of 1 with 2 enhanced the inhibitory effect.

引用

页码：1776 / 1778

页数：3

共 13 条

[1] BNOLMANS, 1972, CANCER RES, V32, P450
[2] INAYAMA YY, 1986, JPN J CANCER RES, V77, P315
[3] STUDIES ON INHIBITORS OF SKIN TUMOR PROMOTION .11. INHIBITORY EFFECTS OF FLAVONOIDS FROM SCUTELLARIA-BAICALENSIS ON EPSTEIN-BARR-VIRUS ACTIVATION AND THEIR ANTI-TUMOR-PROMOTING ACTIVITIES
KONOSHIMA, T
KOKUMAI, M
KOZUKA, M
IINUMA, M
MIZUNO, M
TANAKA, T
TOKUDA, H
NISHINO, H
IWASHIMA, A
[J]. CHEMICAL & PHARMACEUTICAL BULLETIN, 1992, 40 (02) : 531 - 533
[4] KONOSHIMA T, 1989, CHEM PHARM BULL, V37, P2731, DOI 10.1248/cpb.37.2731
[5] STUDIES ON INHIBITORS OF SKIN TUMOR PROMOTION .3. INHIBITORY EFFECTS OF ISOFLAVONOIDS FROM WISTERIA-BRACHYBOTRYS ON EPSTEIN-BARR VIRUS-ACTIVATION
KONOSHIMA, T
OKAMOTO, E
KOZUKA, M
NISHINO, H
TOKUDA, H
TANABE, M
[J]. JOURNAL OF NATURAL PRODUCTS, 1988, 51 (06): : 1266 - 1270
[6] CONSTITUENTS OF LEGUMINOUS PLANTS .13. NEW TRITERPENOID SAPONINS FROM WISTARIA-BRACHYBOTRYS
KONOSHIMA, T
KOZUKA, M
HARUNA, M
ITO, K
[J]. JOURNAL OF NATURAL PRODUCTS, 1991, 54 (03): : 830 - 836
[7] KONOSHIMA T, 1981, J NAT PRODUCTS, V54, P816
[8] INHIBITION OF 12-O-TETRADECANOYLPHORBOL-13-ACETATE-INDUCED INDUCTION IN EPSTEIN-BARR VIRUS EARLY ANTIGEN IN RAJI CELLS
OKAMOTO, H
YOSHIDA, D
MIZUSAKI, S
[J]. CANCER LETTERS, 1983, 19 (01) : 47 - 53
[9] INHIBITORY EFFECTS OF URSOLIC AND OLEANOLIC ACID ON SKIN TUMOR PROMOTION BY 12-O-TETRADECANOYLPHORBOL-13-ACETATE
TOKUDA, H
OHIGASHI, H
KOSHIMIZU, K
ITO, Y
[J]. CANCER LETTERS, 1986, 33 (03) : 279 - 285
[10] TOKUDA H, 1991, ONCOLOGY, V48, P77

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