SYSTEMIC LUPUS-ERYTHEMATOSUS AND CHRONIC LYMPHOCYTIC-LEUKEMIA - RARE COEXISTENCE IN 3 PATIENTS, WITH COMMENTS ON PATHOGENESIS

被引:18
作者
LUGASSY, G
LISHNER, M
POLLIACK, A
机构
[1] Institute of Hematology, Barzilai Medical Center, Jerusalem, Ashkelon
[2] Department of Internal Medicine A, Sapir Medical Center, Meir Hospital, Jerusalem, Kfar Saba
[3] Lymphoma Leukemia Unit, Department of Hematology, Hadassah University Hospital, Jerusalem
关键词
SLE; CLL; AUTOIMMUNE DISORDERS;
D O I
10.3109/10428199209054911
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
We describe three patients with coexistent chronic lymphatic leukemia (CLL) and systemic lupus erythematosus (SLE). In two patients, the CLL was present before or coexistent with the SLE when the SLE was diagnosed, while in the third, the CLL developed 5 years after the diagnosis of SLE was first made. Although the association of autoimmune diseases and lymphoproliferative disorders is well established, only a few patients with coexistent CLL and concomitant SLE have been reported. The possible pathogenesis of this rare association is discussed.
引用
收藏
页码:243 / 245
页数:3
相关论文
共 19 条
[1]  
Miller D.G., The association of immune disease and malignant lymphoma, Ann. Intern. Med., 66, pp. 507-521, (1967)
[2]  
McCarthy G.A., Autoimmunity and malignancy, Med. Clin. North. Am., 69, pp. 599-615, (1985)
[3]  
Sela O., Shoenfeld Y., Cancer in autoimmune diseases, Semir. Arthritis Rehum., 18, pp. 77-78, (1988)
[4]  
Michaeli J., Lugassy G., Raz I., Polliack A., Chronic lymphocytic leukemia, lymphoma and autoimmunity, Chronic Lymphocytic Leukemia, pp. 231-247, (1988)
[5]  
Green J.A., Dawson A.A., Walker W., Systemic lupus erythematosus and lymphoma, The Lancet, 2, pp. 753-758, (1978)
[6]  
Andrew V.C., Zlatkov N.B., Systemic lupus erythematosus and neoplasia of the lymphoreticular system, J. Dermatol., 80, pp. 503-508, (1968)
[7]  
Ho C., Chiang Y., Choug L., Lin H., Hwang T., Development of chronic lymphocytic leukemia in a case of Sjogren's syndrome with systemic lupus erythematosus, Scand. J. Hematol., 35, pp. 246-248, (1988)
[8]  
Hardy R.R., Hayakawa K., Development and physiology of Iy-1B and its human homolog leu-1B, Immunol. Rev., 93, pp. 53-79, (1986)
[9]  
Kipps T.J., The CD5 B cell, Acta Immunol., 47, pp. 117-185, (1989)
[10]  
Plater-Zyberk C., Maini R.N., Lam K., Kennedy T.D., Janossy G., A rheumatoid arthritis B cell subset expresses a phenotype similar to that of chronic lymphocytic leukemia, Arthritis Rheum., 28, pp. 971-976, (1985)