THE ROLE OF METABOLIC-ACTIVATION IN DRUG TOXICITY

[1] BIOSYNTHESIS AND BIOTRANSFORMATION OF GLUTATHIONE S-CONJUGATES TO TOXIC METABOLITES [J]. CRC CRITICAL REVIEWS IN TOXICOLOGY, 1988, 18 (04): : 311 - 341

[2] CLEAVAGE OF S-(1,2-DICHLOROVINYL)-L-CYSTEINE BY AN ENZYME OF BOVINE ORIGIN [J]. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1965, 111 (03) : 593 - +

[3] DNA SEQUENCING OF A MOUSE-LIVER PROTEIN THAT BINDS SELENIUM - IMPLICATIONS FOR SELENIUMS MECHANISM OF ACTION IN CANCER PREVENTION [J]. CARCINOGENESIS, 1990, 11 (11) : 2071 - 2073

[4] BARON J, 1981, ARCH BIOCHEM BIOPHYS, V258, P519

[5] IMMUNOCHEMICAL DETECTION OF ACETAMINOPHEN-BOUND LIVER PROTEINS [J]. BIOCHEMICAL PHARMACOLOGY, 1987, 36 (08) : 1193 - 1196

[6] PURIFICATION, ANTIBODY-PRODUCTION, AND PARTIAL AMINO-ACID-SEQUENCE OF THE 58-KDA ACETAMINOPHEN-BINDING LIVER PROTEINS [J]. TOXICOLOGY AND APPLIED PHARMACOLOGY, 1992, 113 (01) : 19 - 29

[7] HUMAN ANTI-ENDOPLASMIC RETICULUM AUTOANTIBODIES APPEARING IN A DRUG-INDUCED HEPATITIS ARE DIRECTED AGAINST A HUMAN-LIVER CYTOCHROME-P-450 THAT HYDROXYLATES THE DRUG [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1987, 84 (02) : 551 - 555

[8] FORMATION AND PERSISTENCE OF ARYLAMINE DNA ADDUCTS INVIVO [J]. ENVIRONMENTAL HEALTH PERSPECTIVES, 1985, 62 (OCT) : 19 - 30

[9] 2,5-HEXANEDIONE ALTERS MICROTUBULE ASSEMBLY .2. ENHANCED POLYMERIZATION OF CROSS-LINKED TUBULIN [J]. TOXICOLOGY AND APPLIED PHARMACOLOGY, 1987, 88 (03) : 383 - 396

[10] LIVER NECROSIS FROM PARACETAMOL [J]. BRITISH JOURNAL OF PHARMACOLOGY AND CHEMOTHERAPY, 1966, 26 (03): : 606 - &

[1] BIOSYNTHESIS AND BIOTRANSFORMATION OF GLUTATHIONE S-CONJUGATES TO TOXIC METABOLITES [J]. CRC CRITICAL REVIEWS IN TOXICOLOGY, 1988, 18 (04): : 311 - 341

[2] CLEAVAGE OF S-(1,2-DICHLOROVINYL)-L-CYSTEINE BY AN ENZYME OF BOVINE ORIGIN [J]. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1965, 111 (03) : 593 - +

[3] DNA SEQUENCING OF A MOUSE-LIVER PROTEIN THAT BINDS SELENIUM - IMPLICATIONS FOR SELENIUMS MECHANISM OF ACTION IN CANCER PREVENTION [J]. CARCINOGENESIS, 1990, 11 (11) : 2071 - 2073

[4] BARON J, 1981, ARCH BIOCHEM BIOPHYS, V258, P519

[5] IMMUNOCHEMICAL DETECTION OF ACETAMINOPHEN-BOUND LIVER PROTEINS [J]. BIOCHEMICAL PHARMACOLOGY, 1987, 36 (08) : 1193 - 1196

[6] PURIFICATION, ANTIBODY-PRODUCTION, AND PARTIAL AMINO-ACID-SEQUENCE OF THE 58-KDA ACETAMINOPHEN-BINDING LIVER PROTEINS [J]. TOXICOLOGY AND APPLIED PHARMACOLOGY, 1992, 113 (01) : 19 - 29

[7] HUMAN ANTI-ENDOPLASMIC RETICULUM AUTOANTIBODIES APPEARING IN A DRUG-INDUCED HEPATITIS ARE DIRECTED AGAINST A HUMAN-LIVER CYTOCHROME-P-450 THAT HYDROXYLATES THE DRUG [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1987, 84 (02) : 551 - 555

[8] FORMATION AND PERSISTENCE OF ARYLAMINE DNA ADDUCTS INVIVO [J]. ENVIRONMENTAL HEALTH PERSPECTIVES, 1985, 62 (OCT) : 19 - 30

[9] 2,5-HEXANEDIONE ALTERS MICROTUBULE ASSEMBLY .2. ENHANCED POLYMERIZATION OF CROSS-LINKED TUBULIN [J]. TOXICOLOGY AND APPLIED PHARMACOLOGY, 1987, 88 (03) : 383 - 396

[10] LIVER NECROSIS FROM PARACETAMOL [J]. BRITISH JOURNAL OF PHARMACOLOGY AND CHEMOTHERAPY, 1966, 26 (03): : 606 - &