PROTEIN-SYNTHESIS IN ISOLATED HUMAN SKELETAL-MUSCLE TISSUE - EVALUATION OF AN EXPERIMENTAL-MODEL

被引：8

作者：

LUNDHOLM, K

SCHERSTEN, T

机构：

来源：

CLINICAL SCIENCE | 1979年 / 57卷 / 02期

关键词：

D O I：

10.1042/cs0570221

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

Amino acids were incorporated into soluble proteins, myosin and myoglobin at constant rates for at least 4 h on incubation of isolated human skeletal muscle fibres. The time course of incorporation of leucine into proteins not attached to ribosomes was approximately constant, suggesting a continuous termination of proteins. A comparison between estimated pool size of ribosomes and incorporation rate of leucine into proteins indicated that initiation of peptides occurred even in the absence of insulin

引用

页码：221 / 223

页数：3

共 11 条

[1]

DICE JF, 1973, J BIOL CHEM, V248, P4220

[2] INFLUENCE OF AMINO ACID SUPPLY ON RIBOSOMES AND PROTEIN SYNTHESIS OF PERFUSED RAT LIVER [J].