FRUCTOSE 2,6-BISPHOSPHATE IN DEVELOPING RAT-BRAIN

被引：7

作者：

AMBROSIO, S

VENTURA, F

BARTRONS, R

机构：

[1] Unitat de Bioquímica, Departament de Ciències Fisiològiques, Universitat de Barcelona, Barcelona

来源：

DEVELOPMENTAL BRAIN RESEARCH | 1992年 / 66卷 / 02期

关键词：

FRUCTOSE 2,6-BISPHOSPHATE; PHOSPHOFRUCTO-2-KINASE; PHOSPHOFRUCTO-1-KINASE; RAT BRAIN; PERINATAL RAT;

D O I：

10.1016/0165-3806(92)90092-B

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Fructose 2,6-bisphosphate (Fru-2,6-P2) levels and 6-phosphofructo-1-kinase and 6-phosphofructo-2-kinase activities have been studied in rat brain during development from embryonal to adult state. Fru-2,6-P2 increases slightly from day 16 of gestation, reaching a maximum 24 h after birth, remaining quite constant during postnatal development. In contrast with 6-phosphofructo-1-kinase, which increases progressively after the first week of age, 6-phosphofructo-2-kinase remains unaltered throughout the period studied. The role of Fru-2,6-P2 in controlling cerebral glycolysis is discussed.

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收藏

页码：274 / 276

页数：3

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