COMPARISON OF 3 IMMUNOASSAYS FOR THE DETECTION OF ANTI-HHV6

被引：3

作者：

COYLE, PV

BRIGGS, M

TEDDER, RS

FOX, JD

机构：

[1] UCL, DEPT MED MICROBIOL,DIV VIROL,WINDEYER BLDG, 46 CLEVELAND ST, LONDON WIP 6DB, ENGLAND

[2] UNIV LONDON MIDDLESEX HOSP, LONDON WIP 6DB, ENGLAND

[3] ROYAL VICTORIA HOSP, REG VIRUS LAB, BELFAST BT12 6BA, NORTH IRELAND

来源：

JOURNAL OF VIROLOGICAL METHODS | 1992年 / 38卷 / 03期

基金：

英国惠康基金;

关键词：

HUMAN HERPESVIRUS-6; COMPETITIVE RIA; CIRCLE IMMUNOASSAY;

D O I：

10.1016/0166-0934(92)90073-M

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Sera from 96 blood donors were tested for antibody to human herpesvirus 6 by indirect immunofluorescence (IF), circle immunoassay (CIA) and competitive radioimmunoassay (RIA). The correlation between the three assays was good but the CIA and competitive RIA were more sensitive for the detection of HHV6 antibody than indirect IF. The crossreaction of HHV6 antibody with that to the other human herpesviruses was also studied in this blood donor group. No correlation was found between antibody to human herpesvirus 6 by any of the methods described and antibody to any of the other human herpesviruses in these sera.

引用

页码：283 / 295

页数：13

共 16 条

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