ADSORPTION OF CODEINE ON HYDROPHILIC SILICA AND SILICA SURFACE-MODIFIED BY HYDROPHOBIC GROUPS IN THE PRESENCE OF ELECTROLYTES

被引：8

作者：

STRNADOVA, M ^{[1
]}

LEIMBACH, J ^{[1
]}

RUPPRECHT, H ^{[1
]}

机构：

[1] UNIV REGENSBURG,DEPT PHARMACEUT TECHNOL,D-93053 REGENSBURG,GERMANY

来源：

COLLOID AND POLYMER SCIENCE | 1995年 / 273卷 / 07期

关键词：

ADSORPTION; CODEINE; SURFACE MODIFIED; SILICA; ALKYL GROUP; ELECTROLYTE; PH;

D O I：

10.1007/BF00652262

中图分类号：

O64 [物理化学（理论化学）、化学物理学];

学科分类号：

070304 ; 081704 ;

摘要：

The adsorption of codeine from aqueous solution onto colloidal silica and silica surface-modified with chemiadsorbed octadecyl dimethyl silane (ODDMS) or dimethyl silane (DMS) groups was studied in the presence of neutral electrolytes at different pH values. From codeine-hydrochloride solutions codeine cations are strongly bound to negatively charged silica surfaces. Inorganic salts (NaCl, NaNO3) reduce the adsorption of the organic cation. On silica modified by ODDMS (10% of surface silanol groups are occupied), codeine cations are adsorbed to a higher extent at pH 6, while at pH 8 the adsorbed amounts are lower than on the bare silica surface. Neutral electrolytes reduce codeine adsorption on the ODDMS modified silica. On the hydrophobic silica, completely covered by DMS groups, codeine adsorption is considerably lower than on the bare silica, but neutral salts increase the adsorption. The adsorption of codeine is compared with the adsorption of aggregating surfactant ions. Common and different features of their interactions with silica surfaces are outlined.

引用

页码：687 / 692

页数：6

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