ESTROGEN-TREATMENT OF POST-MENOPAUSAL VAGINAL ATROPHY - CYTOLOGICAL ASSESSMENT

被引:4
作者
HUSTIN, J
DRYKONINGEN, GJA
机构
[1] INST MORPHOL PATHOL,B-6270 LOVERVAL,BELGIUM
[2] ORGANON SCI DEV GRP,DEPT MED SERV,OSS,NETHERLANDS
关键词
Cytology; Endometrial biopsy; Estriol estrogens; Postmenopause; Vaginal atrophy;
D O I
10.1016/0378-5122(79)90010-0
中图分类号
R592 [老年病学]; C [社会科学总论];
学科分类号
03 ; 0303 ; 100203 ;
摘要
The following is an assessment of the maturation value (MV) based upon cytohormonal smears of postmenopausal or hysterectomized patients: 1. (1) There is a negative correlation between the MV and the number of postmenopausal years. 2. (2) There is a positive correlation between MV values higher than 60 and urinary excretion of estrogens. 3. (3) The MV is ideally suited to demonstrate the beneficial effect of various estrogens on the vaginal mucosa. 4. (4) Though its action is delayed, and necessitates a threshold dose of 33 μg/kg weight/wk, estriol might be considered as the drug of choice for a beneficial effect on the vaginal mucosa, because of its lack of endometrial action at this dosage. © 1979.
引用
收藏
页码:207 / 213
页数:7
相关论文
共 4 条
[1]   FURTHER OBSERVATIONS ON KOBER COLOUR AND ITTRICH FLUORESCENCE REACTIONS IN MEASUREMENT OF OESTRIOL OESTRONE AND OESTRADIOL [J].
BROWN, JB ;
MACNAUGHTAN, C ;
SMITH, MA ;
SMYTH, B .
JOURNAL OF ENDOCRINOLOGY, 1968, 40 (02) :175-+
[2]  
HUSTIN J, 1977, ACTA CYTOL, V21, P225
[3]  
HUSTIN J, 1973, REV FR CYTOL CLIN, V6, P17
[4]  
LAURITZEN C, 1973, AGEING ESTROGENS