HEMIN - AN INHIBITOR OF ERYTHROID CELL RIBONUCLEASE

被引：22

作者：

BURKA, ER

机构：

[1] Cardeza Foundation for Hematologic Research, Jefferson Medical College, Philadelphia

来源：

SCIENCE | 1968年 / 162卷 / 3859期

关键词：

D O I：

10.1126/science.162.3859.1287

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Hemin, in concentrations which stimulate protein synthesis and stabilize polyribosomes in reticulocytes, is a potent inhibitor of ribonuclease activity in the erythroid cell. This may offer a partial explanation for the way in which hemin acts to accelerate globin synthesis and thus synchronize the synthesis of hemin and globin in the maturing erythroid cell.

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页码：1287 / &

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