COHESIVE STRENGTH OF CORNEAL LAMELLAE

被引：39

作者：

MAURICE, DM

MONROE, F

机构：

[1] Department of Ophthalmology, Stanford University Medical Center, Stanford

来源：

EXPERIMENTAL EYE RESEARCH | 1990年 / 50卷 / 01期

关键词：

biomechanics; cohesive strength; collagen-polysaccharide interaction; cornea; growth factors; keratoplasty; stroma; wound healing;

D O I：

10.1016/0014-4835(90)90011-I

中图分类号：

R77 [眼科学];

学科分类号：

100212 ;

摘要：

Strips of rabbit stroma were prepared, and the force required to tear them apart along their length was determined. This amounted to an average of 10 g mm-1 width of tissue and it is independent of the depth of the plane in which the splitting of the cornea takes place. It could not be determined, however, whether the cohesive strength of the tissue is due to occasional collagen fibrils binding it together, interweaving of the lamellae or enmeshing of the collagen fibrils by ground substances. Other corneas were split by blunt dissection in vivo and allowed to recover for various periods of time, when the reformed strength of the split was measured. It was found to be negligible for about 5 days and rose quickly to 0·25-0·5 of the value of the untouched cornea. No increase in the force of adhesion of the split stroma was observed if an extract of corneal epithelium or a suspension of platelets was injected into the wound. © 1990.

引用

页码：59 / 63

页数：5