RELIEF OF CHRONIC BURNING PAIN IN FABRY DISEASE WITH NEUROTROPIN

被引:21
作者
INAGAKI, M
OHNO, K
OHTA, S
SAKURABA, H
TAKESHITA, K
机构
[1] Division of Child Neurology, Institute of Neurological Sciences, Tottori University School of Medicine, Yonago
[2] Department of Pediatrics, Matsue Red Cross Hospital, Matsue
[3] Department of Clinical Genetics, Tokyo Metropolitan Institute of Medical Science, Tokyo
关键词
D O I
10.1016/0887-8994(90)90067-B
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Neurotropin, an extract from the inflamed skin of vaccinia virus-inoculated rabbits, was effective in the relief of sharp or burning pain induced by pyrexia, hot weather, bathing, or exercise in 2 siblings with Fabry disease. Neither neurotropin nor carbamazepine monotherapy relieved the episodic colicky pain in 1 patient; however, therapy with both drugs eliminated the pain completely. This result suggests that the mechanisms underlying the analgesic actions of both drugs may be complementary in ameliorating the pain of Fabry disease, even though the mechanism underlying the pain has not been clearly elucidated. © 1990.
引用
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页码:211 / 213
页数:3
相关论文
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