ELECTRICAL-STIMULATION OF CULTURED MYOCARDIAL-CELLS

被引：9

作者：

MITCHELL, RH

BAILEY, AH

ANDERSON, JM

GILMORE, WS

机构：

[1] UNIV ULSTER,NO IRELAND BIOENGN CTR,NEWTOWNABBEY,NORTH IRELAND

[2] UNIV ULSTER,DEPT BIOL & BIOMED SCI,NEWTOWNABBEY,NORTH IRELAND

来源：

JOURNAL OF BIOMEDICAL ENGINEERING | 1992年 / 14卷 / 01期

关键词：

CARDIAC MUSCLE; MONOLAYER; STIMULATION; CELLULAR RESPONSE;

D O I：

10.1016/0141-5425(92)90035-J

中图分类号：

R318 [生物医学工程];

学科分类号：

0831 ;

摘要：

This paper reports on the use of a cardiac tissue monolayer model in the investigation of some of the fundamental electrical properties of cardiac muscle. The response of cardiac tissue to increasing levels of electrical stimulus is investigated and the strength-duration curve for rectangular waveform stimulation is measured. An experimental protocol is established which provides for uniform field stimulation of the cells, and allows the cellular response (contraction) to be recorded.

引用

页码：52 / 56

页数：5

共 13 条

[1]

Blair HA, 1932, J GEN PHYSIOL, V15, P731, DOI 10.1085/jgp.15.6.731

[2] On the intensity-time relations for stimulation by electric currents. I [J].