NEW BIOACTIVE METABOLITES FROM A FRESH-WATER ISOLATE OF THE FUNGUS KIRSCHSTEINIOTHELIA SP

被引：41

作者：

POCH, GK

GLOER, JB

SHEARER, CA

机构：

[1] UNIV IOWA,DEPT CHEM,IOWA CITY,IA 52242

[2] UNIV ILLINOIS,DEPT PLANT BIOL,URBANA,IL 61801

来源：

JOURNAL OF NATURAL PRODUCTS | 1992年 / 55卷 / 08期

关键词：

D O I：

10.1021/np50086a010

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

The new cytotoxic naphthoquinone dimer kirschsteinin [5], two new chlorinated diphenyl ethers 8 and 9, three known naphthoquinone derivatives 1, 2, and 7, a monoacetyl derivative of 2, and the (-)-enantiomer of O-methylasparvenone [4), have been isolated from a previously undescribed species of Kirschsteiniothelia. The structures of these compounds were assigned primarily by nmr studies and by spectral comparisons.

引用

收藏

页码：1093 / 1099

页数：7

相关论文

共 12 条

[1]

ALLEY MC, 1988, CANCER RES, V48, P589

[2] STRUCTURE DETERMINATION AND SPECTRAL ASSIGNMENT BY PULSED POLARIZATION TRANSFER VIA LONG-RANGE H-1-C-13 COUPLINGS [J].

BAX, A .

JOURNAL OF MAGNETIC RESONANCE, 1984, 57 (02) :314-318

[3] 6-ETHYL-5-HYDROXY-2,7-DIMETHOXY-1,4-NAPHTHOQUINONE FROM HENDERSONULA-TORULOIDEA - A BIOSYNTHETIC STUDY USING C-13 LABELS DETECTED BY NUCLEAR MAGNETIC-RESONANCE AND C-14 TRACERS [J].

BENTLEY, R ;

BANACH, WJ ;

MCINNES, AG ;

WALTER, JA .

BIOORGANIC CHEMISTRY, 1981, 10 (04) :399-411

[4] STEP GRADIENT ELUTION IN GEL-PERMEATION CHROMATOGRAPHY - A NEW APPROACH TO NATURAL-PRODUCTS SEPARATIONS [J].

CARDELLINA, JH .

JOURNAL OF NATURAL PRODUCTS, 1983, 46 (02) :196-199

[5]

CHAO PD, 1975, LLOYDIA, V38, P213

[6] KIRSCHSTEINIOTHELIA, A NEW GENUS FOR THE MICROTHELIA-INCRUSTANS-GROUP (DOTHIDEALES) [J].

HAWKSWORTH, DL .

BOTANICAL JOURNAL OF THE LINNEAN SOCIETY, 1985, 91 (1-2) :181-202

[7]

HIGA M, 1988, CHEM PHARM BULL, V36, P3234

[8] POLHYDROXYNAPHTHOQUINONES - PREPARATION AND HYDROLYSIS OF METHOXYL DERIVATIVES [J].

MOORE, RE ;

SINGH, H ;

CHANG, CWJ ;

SCHEUER, PJ .

TETRAHEDRON, 1967, 23 (08) :3271-&

[9] NOVEL PHYTOTOXINS PRODUCED BY THE CAUSAL FUNGUS OF THE SHOOT BLIGHT OF LARCHES [J].

OTOMO, N ;

SATO, H ;

SAKAMURA, S .

AGRICULTURAL AND BIOLOGICAL CHEMISTRY, 1983, 47 (05) :1115-1119

[10] HELICASCOLIDE-A AND HELICASCOLIDE-B - NEW LACTONES FROM THE MARINE FUNGUS HELICASCUS-KANALOANUS [J].

POCH, GK ;

GLOER, JB .

JOURNAL OF NATURAL PRODUCTS, 1989, 52 (02) :257-260