THE 62 MEV PROTON-BEAM FOR THE TREATMENT OF OCULAR MELANOMA AT CLATTERBRIDGE

被引:50
作者
BONNETT, DE [1 ]
KACPEREK, A [1 ]
SHEEN, MA [1 ]
GOODALL, R [1 ]
SAXTON, TE [1 ]
机构
[1] CLATTERBRIDGE HOSP, MRC, CYCLOTRON UNIT, BEBINGTON L63 9NY, MERSEYSIDE, ENGLAND
关键词
D O I
10.1259/0007-1285-66-790-907
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
A second treatment room and beam line has been constructed at the Cyclotron Unit at Clatterbridge for the purpose of using 62 MeV protons for the treatment of ocular melanoma. A uniform beam is produced by a double foil scattering system. The initial Bragg peak is spread across the target volume by the use of beam modulators. These are rotating four-vaned stepped absorbers made from Perspex. Two beam lines can be configured with different positions of modulators and range limiters. The first has a maximum penetration of 31.9 +/- 0.2 mm in water and the second a penetration of 31.2 +/- 0.2 mm. The second configuration has the advantage of less variation in beam penumbra, with a typical value of 1.7 +/- 0.1 mm for the 90% to 10% decrement lines. The patients are treated with individually shaped collimators. Beam output varies by less than 2% over the range of collimator areas used. The resulting whole-body dose equivalent to patient has also been assessed. In the first three years of operation over 250 patients have been treated.
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页码:907 / 914
页数:8
相关论文
共 17 条
[1]  
ARO ACA, 1991, 2ND P EUR PART ACC C, pS17
[2]  
BONNETT DE, 1991, RADIAT PROT DOSIM, V37, P95
[3]  
CHU WT, 1988, EUR12165EN COMM EUR
[4]  
COSGROVE VP, 1992, RADIAT PROT DOSIM, V44, P405
[5]   ENERGY OF PROTON ACCELERATOR NECESSARY FOR TREATMENT OF CHOROIDAL MELANOMAS [J].
GOITEIN, M ;
GENTRY, R ;
KOEHLER, AM .
INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS, 1983, 9 (02) :259-260
[6]   PLANNING PROTON THERAPY OF THE EYE [J].
GOITEIN, M ;
MILLER, T .
MEDICAL PHYSICS, 1983, 10 (03) :275-283
[7]  
GOTTSCHALK B, 1986, PTA8186 HARV CYCL LA
[8]  
GRAGOUDAS ES, 1980, OPHTHALMOLOGY, V87, P571
[9]   PROTON IRRADIATION OF CHOROIDAL MELANOMAS - PRELIMINARY-RESULTS [J].
GRAGOUDAS, ES ;
GOITEIN, M ;
KOEHLER, A ;
CONSTABLE, IJ ;
WAGNER, MS ;
VERHEY, L ;
TEPPER, J ;
SUIT, HD ;
BROCKHURST, RJ ;
SCHNEIDER, RJ ;
JOHNSON, KN .
ARCHIVES OF OPHTHALMOLOGY, 1978, 96 (09) :1583-1591
[10]  
Janni J. F., 1982, Atomic Data and Nuclear Data Tables, V27, P147, DOI 10.1016/0092-640X(82)90004-3