PEGA - A FLOW STABLE POLYETHYLENE-GLYCOL DIMETHYL ACRYLAMIDE COPOLYMER FOR SOLID-PHASE SYNTHESIS

被引：291

作者：

MELDAL, M

机构：

[1] Carlsberg Laboratory, Department of Chemistry, 2500 Valby, Copenhagen

来源：

TETRAHEDRON LETTERS | 1992年 / 33卷 / 21期

关键词：

D O I：

10.1016/S0040-4039(00)79604-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A copolymer of bisacrylamido polyethylene glycol, monoacrylamido polyethylene glycol and N,N-dimethyl acrylamide was synthesized by radical polymerization and characterized for peptide synthesis by preparation of the difficult test sequence 65-74 from the acyl carrier protein. Reaction times were recorded and compared with synthesis on kieselguhr supported polydimethyl acrylamide gel.

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页码：3077 / 3080

页数：4

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