DEMYELINATING PERIPHERAL NEUROPATHY IN CREUTZFELDT-JAKOB DISEASE

被引：50

作者：

NEUFELD, MY

JOSIPHOV, J

KORCZYN, AD

机构：

[1] TEL AVIV UNIV, SACKLER FAC MED, TEL AVIV SOURASKY MED CTR, DEPT NEUROL, IL-69978 TEL AVIV, ISRAEL

[2] TEL AVIV UNIV, SACKLER FAC MED, TEL AVIV SOURASKY MED CTR, DEPT PATHOL, IL-69978 TEL AVIV, ISRAEL

来源：

MUSCLE & NERVE | 1992年 / 15卷 / 11期

关键词：

CREUTZFELDT-JAKOB DISEASE; PRIONS; PERIPHERAL NEUROPATHY; DEMYELINATING NEUROPATHY;

D O I：

10.1002/mus.880151103

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

We desribe 2 patients of Jewish Libyan descent, who presented with a clinical syndrome compatible with Creutzfeldt-Jakob disease and who were found to have a mutation of codon 200 in the prion protein. The patients developed symptoms and signs of peripheral nerve involvement diagnosed by electrodiagnostic and histopathological studies as demyelinating neuropathy. This may be a rare manifestation of Creutzfeldt-Jakob disease.

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页码：1234 / 1239

页数：6

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