A NOVEL FAMILY-C OF THE GENES THAT ENCODE BOMBYXIN, AN INSULIN-RELATED BRAIN SECRETORY PEPTIDE OF THE SILKMOTH BOMBYX-MORI - ISOLATION AND CHARACTERIZATION OF GENE-C-1

被引：33

作者：

IWAMI, M

ADACHI, T

KONDO, H

KAWAKAMI, A

SUZUKI, Y

NAGASAWA, H

SUZUKI, A

ISHIZAKI, H

机构：

[1] UNIV TOKYO,FAC AGR,DEPT AGR CHEM,TOKYO 113,JAPAN

[2] NATL INST BASIC BIOL,OKAZAKI,AICHI 444,JAPAN

来源：

INSECT BIOCHEMISTRY | 1990年 / 20卷 / 03期

关键词：

Bombyx mori; bombyxin; brain neurosecretory hormone; insulin; processed gene;

D O I：

10.1016/0020-1790(90)90047-X

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A novel gene C-1 encoding bombyxin, an insulin-family peptide which is produced by the brain neurosecretory cells of the silkmoth Bombyx mori, has been cloned and characterized. The nucleotide sequence of this gene and the deduced amino acid sequence are definitely different from those previously characterized for the A- and B-family bombyxin genes. Southern hybridization indicates that the Bombyx genome contains multiple gene copies closely related to this gene comprising a novel family C. Tertiary structural and functional features of bombyxins are speculated from their primary structure. Inspection of the sequences of the bombyxin genes so far characterized suggests that they may be the functional processed genes. © 1990.

引用

页码：295 / &

共 35 条

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