ATROPISOMERISM OF 1-ALKYLCYCLOHEPTA[B]PYRROL-2(1H)-ONES - ISOLATION OF THE ROTATIONAL ISOMERS OF 1-(2,4-DIMETHYL-3-PENTYL)CYCLOHEPTA[B]PYRROL-2(1H)-ONE

被引：1

作者：

IKEDA, Y ^{[1
]}

KATO, N ^{[1
]}

MORI, A ^{[1
]}

TAKESHITA, H ^{[1
]}

机构：

[1] KYUSHU UNIV 86,INST ADV MAT STUDY,KASUGA,FUKUOKA 816,JAPAN

来源：

MAGNETIC RESONANCE IN CHEMISTRY | 1992年 / 30卷 / 06期

关键词：

ATROPISOMERIZATION OF THE C-N BOND; CYCLOHEPTA[B]PYRROL-2(1H)-ONES; POSITIVE BUTTRESSING EFFECT;

D O I：

10.1002/mrc.1260300604

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

1-Alkylcyclohepta[b]pyrrol-2(1H)-ones showed rotational isomerism around the C-N bond. Two rotamers of the 1-(2,4-dimethyl-3-pentyl) derivative were isolable by high-performance liquid chromatography at 0-degrees-C. The activation free energy, measured by the line-shape analysis of the variable-temperature NMR spectra, was 86.8 kJ mol-1 at 25-degrees-C. In a bromo derivative, a positive buttressing effect was observed.

引用

页码：476 / 480

页数：5

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