POTENTIATION OF THE EFFECTS OF CHLORHEXIDINE DIACETATE AND CETYLPYRIDINIUM CHLORIDE ON MYCOBACTERIA BY ETHAMBUTOL

被引:19
作者
BROADLEY, SJ
JENKINS, PA
FURR, JR
RUSSELL, AD
机构
[1] UNIV WALES COLL CARDIFF,WELSH SCH PHARM,CARDIFF CF1 3XF,S GLAM,WALES
[2] UNIV WALES HOSP,PUBL HLTH LAB SERV,MYCOBACTERIUM REFERENCE UNIT,CARDIFF CF4 4XW,S GLAM,WALES
关键词
D O I
10.1099/00222615-43-6-458
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
Ethambutol enhanced the effects of chlorhexidine diacetate and cetylpyridinium chloride against Mycobacterium avium, M. bovis BCG, M. fortuitum and M. phlei. The findings show that it is possible to increase the susceptibility of mycobacteria to agents that normally exhibit poor activity against these organisms because of their reduced cellular penetration.
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页码:458 / 460
页数:3
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