STEREOCHEMISTRY OF ALPHA-OXIDATION OF FATTY ACIDS IN PLANTS - STEREOCHEMISTRY OF BIOSYNTHESIS OF LONG-CHAIN 2-HYDROXYACIDS

被引：24

作者：

MORRIS, LJ

HITCHCOCK, C

机构：

[1] Unilever Research Laboratories, Bedford, Colworth House, Sharnbrook

来源：

EUROPEAN JOURNAL OF BIOCHEMISTRY | 1968年 / 4卷 / 02期

关键词：

D O I：

10.1111/j.1432-1033.1968.tb00185.x

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

When [1‐14C]palmitic acid is incubated with young pea leaves, or solutions of their acetonedried powders, d‐2‐hydroxy[1‐14C]palmitic acid accumulates. When l‐[1‐14C, 2‐3H]palmitic acid is similarly oxidised, d‐2‐hydroxy[1‐14C]palmitate is formed which retains the tritium (99% retention). When d‐[1‐14C, 2‐3H]palmitic acid is similarly oxidised, d‐2‐hydroxy [1‐14C]palmitate is formed with loss of tritium (24% retention). The mechanism of α‐hydroxylation is therefore replacement of α‐hydrogen by hydroxyl with overall retention of configuration. Copyright © 1968, Wiley Blackwell. All rights reserved

引用

页码：146 / +

页数：1

共 8 条

[1] FOLCH J, 1957, J BIOL CHEM, V226, P497
[2] STEREOCHEMISTRY OF SOME LITHIUM ALUMINUM DEUTERIDE REDUCTIONS
HELMKAMP, GK
RICKBORN, BF
[J]. JOURNAL OF ORGANIC CHEMISTRY, 1957, 22 (05) : 479 - 482
[3] MECHANISM OF ALPHA-OXIDATION IN LEAVES
HITCHCOC.C
JAMES, AT
[J]. BIOCHIMICA ET BIOPHYSICA ACTA, 1966, 116 (03) : 413 - &
[4] STEREOCHEMISTRY OF ALPHA-OXIDATION OF FATTY ACIDS IN PLANTS - ISOTOPE COMPETITION EXPERIMENTS
HITCHCOCK, C
MORRIS, LJ
JAMES, AT
[J]. EUROPEAN JOURNAL OF BIOCHEMISTRY, 1968, 3 (04): : 419 - +
[5] STEREOCHEMISTRY OF ALPHA-OXIDATION OF FATTY ACIDS IN PLANTS - CONFIGURATION OF BIOSYNTHETIC LONG-CHAIN 2-HYDROXYACIDS
HITCHCOCK, C
MORRIS, LJ
JAMES, AT
[J]. EUROPEAN JOURNAL OF BIOCHEMISTRY, 1968, 3 (04): : 473 - +
[6] HITCHCOCK C, 1964, J LIPID RES, V5, P593
[7] WOOL WAX .6. THE SYNTHESIS AND STEREOCHEMISTRY OF THE STRAIGHT-CHAIN ALPHA-HYDROXY-ACIDS
HORN, DHS
PRETORIUS, YY
[J]. JOURNAL OF THE CHEMICAL SOCIETY, 1954, (MAY): : 1460 - 1464
[8] SCHROEPF.GJ, 1965, J BIOL CHEM, V240, P54

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