QUANTITATIVE STRUCTURE-ACTIVITY-RELATIONSHIPS .7. BILINEAR MODEL, A NEW MODEL FOR NONLINEAR DEPENDENCE OF BIOLOGICAL-ACTIVITY ON HYDROPHOBIC CHARACTER

被引：199

作者：

KUBINYI, H ^{[1
]}

机构：

[1] KNOLL AG,RES INST,D-6700 LUDWIGSHAFEN,FED REP GER

来源：

JOURNAL OF MEDICINAL CHEMISTRY | 1977年 / 20卷 / 05期

关键词：

D O I：

10.1021/jm00215a002

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

收藏

页码：625 / 629

页数：5

相关论文

共 27 条

[1] Daniel C., 1971, FITTING EQUATIONS DA
[2] DRAPER N, 1966, APPLIED REGRESSION A
[3] The use of chemical potentials as indices of toxicity
Ferguson, J
[J]. PROCEEDINGS OF THE ROYAL SOCIETY SERIES B-BIOLOGICAL SCIENCES, 1939, 127 (848): : 387 - 404
[4] FRANKE R, 1973, ACTA BIOL MED GER, V31, P273
[5] HANSCH C, 1971, MOL PHARMACOL, V7, P337
[6] HANSCH C, 1965, MOL PHARMACOL, V1, P205
[7] LIPOPHILIC CHARACTER AND BIOLOGICAL-ACTIVITY OF DRUGS .2. PARABOLIC CASE
HANSCH, C
CLAYTON, JM
[J]. JOURNAL OF PHARMACEUTICAL SCIENCES, 1973, 62 (01) : 1 - 21
[8] LINEAR RELATIONSHIPS BETWEEN LIPOPHILIC CHARACTER AND BIOLOGICAL-ACTIVITY OF DRUGS
HANSCH, C
DUNN, WJ
[J]. JOURNAL OF PHARMACEUTICAL SCIENCES, 1972, 61 (01) : 1 - &
[9] RHO-SIGMA-PI ANALYSIS . METHOD FOR CORRELATION OF BIOLOGICAL ACTIVITY + CHEMICAL STRUCTURE
HANSCH, C
FUJITA, T
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1964, 86 (08) : 1616 - &
[10] A QUANTITATIVE APPROACH TO BIOCHEMICAL STRUCTURE-ACTIVITY RELATIONSHIPS
HANSCH, C
[J]. ACCOUNTS OF CHEMICAL RESEARCH, 1969, 2 (08) : 232 - &