PREPARATION OF 3-ACETAMIDO-2,5-DIHYDROTHIOPHENES

被引：3

作者：

FIELD, GF ^{[1
]}

机构：

[1] F HOFFMANN LA ROCHE & CO LTD, CH-4002 BASEL, SWITZERLAND

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1979年 / 44卷 / 05期

关键词：

D O I：

10.1021/jo01319a035

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Heating of N-acetyl-S-(α-ketoalkyl)cysteines with acetic anhydride gives 3-acetamido-2, 5-dihydrothiophenes. Under other conditions two types of undecarboxylated thiophene derivatives, 5 and 6, have been obtained. © 1979, American Chemical Society. All rights reserved.

引用

页码：825 / 827

页数：3

共 12 条

[1] BIOTIN .4. A 2ND SYNTHESIS OF 2-7DELTA-CARBOXYBUTYL)-THIOPHANE-3,4-DICARBOXYLIC ACID [J].

BAKER, BR ;

QUERRY, MV ;

BERNSTEIN, S ;

SAFIR, SR ;

SUBBAROW, Y .

JOURNAL OF ORGANIC CHEMISTRY, 1947, 12 (01) :167-173

[2]

CARTER HE, 1946, ORG REACTIONS, V3, P198

[3]

JONES JB, 1971, CAN J CHEM, V49, P3013

[4] NEW HORIZONS IN CARBONYL CHEMISTRY - REAGENTS FOR NUCLEOPHILIC ACYLATION [J].

LEVER, OW .

TETRAHEDRON, 1976, 32 (16) :1943-1971

[5] PHASE-TRANSFER CATALYZED SYNTHESES - 5-THIACYCLOHEXENECARBOXALDEHYDES AND 3,4-EPOXY-2,5-DIHYDROTHIOPHENES [J].

MCINTOSH, JM ;

KHALIL, H .

JOURNAL OF ORGANIC CHEMISTRY, 1977, 42 (12) :2123-2126

[6] DIHYDROTHIOPHENES .4. STEREOCHEMISTRY OF DIHYDROTHIOPHENE FORMATION FROM VINYLPHOSPHONIUM SALTS [J].

MCINTOSH, JM ;

MASSE, GM .

JOURNAL OF ORGANIC CHEMISTRY, 1975, 40 (09) :1294-1298

[7] DIHYDROTHIOPHENES .3. PREPARATION OF SOME 3,4-UNSUBSTITUTED EXAMPLES [J].

MCINTOSH, JM ;

STEEVENS.RS .

CANADIAN JOURNAL OF CHEMISTRY-REVUE CANADIENNE DE CHIMIE, 1974, 52 (10) :1934-1936

[8] DIHYDROTHIOPHENES .2. PREPARATION AND PROPERTIES OF SOME ALKYLATED 2,5-DIHYDROTHIOPHENES [J].

MCINTOSH, JM ;

GOODBRAN.HB ;

MASSE, GM .

JOURNAL OF ORGANIC CHEMISTRY, 1974, 39 (02) :202-206

[9]

SEEBACH D, 1974, CHEM IND-LONDON, P687

[10] ALKYLATION AND MICHAEL ADDITIONS OF GLYCINE ETHYL-ESTER - USE IN ALPHA-AMINO-ACID SYNTHESIS AND AS ACYL CARBANION EQUIVALENT [J].

STORK, G ;

LEONG, AYW ;

TOUZIN, AM .

JOURNAL OF ORGANIC CHEMISTRY, 1976, 41 (21) :3491-3493

← 1 2 →