CIRCADIAN-RHYTHM OF SEROTONIN N-ACETYLTRANSFERASE ACTIVITY IN ORGAN-CULTURE OF CHICKEN PINEAL-GLAND

被引：180

作者：

DEGUCHI, T

机构：

[1] Department of Medical Chemistry, Tokyo Metropolitan Institute for Neurosciences

来源：

SCIENCE | 1979年 / 203卷 / 4386期

关键词：

D O I：

10.1126/science.424750

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

When chicken pineal glands were organ-cultured in darkness, serotonin N-acetyltransferase activity was low during daytime, increased at midnight, and decreased on the next morning. The autonomous increase of N-acetyltransferase activity was suppressed by illumination of the glands. When pineal glands were cultured under a light-dark cycle (LD 12:12), the change of N-acetyltransferase activity continued to oscillate in phase with the light-dark cycle for 3 days.

引用

收藏

页码：1245 / 1247

页数：3

相关论文

共 29 条

[1] PINEAL-GLAND - NEUROCHEMICAL TRANSDUCER [J].

AXELROD, J .

SCIENCE, 1974, 184 (4144) :1341-1348

[2]

BINKLEY S, 1976, FED PROC, V35, P2347

[3] REGULATION OF PINEAL RHYTHMS IN CHICKENS - REFRACTORY PERIOD AND NONVISUAL LIGHT PERCEPTION [J].

BINKLEY, S ;

MACBRIDE, SE ;

KLEIN, DC ;

RALPH, CL .

ENDOCRINOLOGY, 1975, 96 (04) :848-853

[4] PINEAL N-ACETYLTRANSFERASE IN CHICKENS - RHYTHM PERSISTS IN CONSTANT DARKNESS [J].

BINKLEY, S ;

GELLER, EB .

JOURNAL OF COMPARATIVE PHYSIOLOGY, 1975, 99 (01) :67-70

[5] PINEAL ENZYMES - REGULATION OF AVIAN MELATONIN SYNTHESIS [J].

BINKLEY, S ;

MACBRIDE, SE ;

KLEIN, DC ;

RALPH, CL .

SCIENCE, 1973, 181 (4096) :273-275

[6] PINEAL FUNCTION IN SPARROW - CIRCADIAN RHYTHMS AND BODY TEMPERATURE [J].

BINKLEY, S ;

KLUTH, E ;

MENAKER, M .

SCIENCE, 1971, 174 (4006) :311-+

[7] PINEAL-GLAND - BIOLOGICAL CLOCK INVITRO [J].

BINKLEY, SA ;

RIEBMAN, JB ;

REILLY, KB .

SCIENCE, 1978, 202 (4373) :1198-1201

[8] SENSITIVE ASSAY FOR SEROTONIN N-ACETYLTRANSFERASE ACTIVITY IN RAT PINEAL [J].

DEGUCHI, T ;

AXELROD, J .

ANALYTICAL BIOCHEMISTRY, 1972, 50 (01) :174-&

[9] CONTROL OF CIRCADIAN CHANGE OF SEROTONIN N-ACETYLTRANSFERASE ACTIVITY IN PINEAL ORGAN BY BETA-ADRENERGIC RECEPTOR [J].

DEGUCHI, T ;

AXELROD, J .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1972, 69 (09) :2547-&

[10] INDUCTION AND SUPERINDUCTION OF SEROTONIN N-ACETYLTRANSFERASE BY ADRENERGIC DRUGS AND DENERVATION IN RAT PINEAL ORGAN [J].

DEGUCHI, T ;

AXELROD, J .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1972, 69 (08) :2208-&