STRUCTURE-ACTIVITY-RELATIONSHIPS OF SYNTHETIC DIOSGENYL MONOGLYCOSIDES

被引：15

作者：

TAKECHI, M

TANAKA, Y

机构：

[1] Faculty of Pharmaceutical Sciences, Kinki University, Higashiosaka

来源：

PHYTOCHEMISTRY | 1991年 / 30卷 / 08期

关键词：

STRUCTURE-ACTIVITY RELATIONSHIPS; HEMOLYSIS; ANTIFUNGAL ACTIVITY; SYNTHETIC MONOGLYCOSIDES; DIOSGENIN; CHOLESTEROL;

D O I：

10.1016/0031-9422(91)85099-L

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Hemolytic or antifungal activities of seven synthetic diosgenyl and three cholesteryl monoglycosides were compared with each other. The hemolytic activities of these glycosides were as weak as those of their aglycones, but the antifungal activities of diosgenyl glucoside and galactoside were much higher than those of the other glycosides. The E and F rings of diosgenin are important for activity.

引用

页码：2557 / 2558

页数：2

共 4 条

[1] C-13 NMR SPECTRAL INVESTIGATIONS .10. C-13 NMR-SPECTROSCOPY OF STEROIDAL SAPOGENINS AND STEROIDAL SAPONINS [J].