MODELING AND SIMULATION OF FRACTIONAL PRECIPITATION - COMPARISON WITH PILOT-PLANT DATA

被引：8

作者：

CLARKSON, AI

BOGLE, IDL

TITCHENERHOOKER, NJ

机构：

[1] Advanced Centre for Biochemical Engineering, Dept of Chemical and Biochemical Engineering, University College London, London, WC1E 7JE, Torrington Place

来源：

COMPUTERS & CHEMICAL ENGINEERING | 1992年 / 16卷

关键词：

MODELING; SIMULATION; PRECIPITATION; CENTRIFUGATION; SOLUBILITY; POPULATION BALANCE; GRADE EFFICIENCY;

D O I：

10.1016/S0098-1354(09)80052-5

中图分类号：

TP39 [计算机的应用];

学科分类号：

081203 ; 0835 ;

摘要：

This paper describes the modelling and simulation of fractional precipitation and centrifugation, two common operations in the downstream processing of intracellular proteins, and demonstrates how the developed models are validated against pilot plant scale data.

引用

页码：S441 / S447

页数：7

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