BENIGN MIXED TUMOR OF CANINE MAMMARY-GLAND SHOWING AN R(X) AND TRISOMY-5 AS THE ONLY CLONAL ABNORMALITIES

被引：12

作者：

BARTNITZKE, S ^{[1
]}

MOTZKO, H ^{[1
]}

ROSENHAGEN, C ^{[1
]}

BULLERDIEK, J ^{[1
]}

机构：

[1] UNIV BREMEN,CTR HUMAN GENET & GENET COUNSELLING,W-2800 BREMEN 33,GERMANY

来源：

CANCER GENETICS AND CYTOGENETICS | 1992年 / 62卷 / 01期

关键词：

D O I：

10.1016/0165-4608(92)90033-5

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

We report a benign mixed tumor of the canine mammary gland which showed an r(X) and trisomy 5 as the only clonal karyotypic deviations. Clonal aberrations were observed in 79 of 160 of the metaphases. Of these, 48 cells had both the r(X) and trisomy 5, whereas the remaining metaphases were characterized by the r(X) as the only clonal aberration. We conclude that formation of the ring chromosome was the first abnormality, followed by trisomy 5 during the course of karyotypic evolution.

引用

页码：29 / 31

页数：3

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