ENANTIOSELECTIVE PALLADIUM CATALYZED ALLYLIC SUBSTITUTION WITH THIENYL OXAZOLINE LIGANDS

被引：117

作者：

FROST, CG ^{[1
]}

WILLIAMS, JMJ ^{[1
]}

机构：

[1] LOUGHBOROUGH UNIV TECHNOL,DEPT CHEM,LOUGHBOROUGH LE11 3TU,LEICS,ENGLAND

来源：

TETRAHEDRON LETTERS | 1993年 / 34卷 / 12期

关键词：

D O I：

10.1016/S0040-4039(00)91990-7

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Homochiral thienyl oxazolines have been employed as ligands for enantioselective palladium catalysed allylic substitution. The ligands are straightforward to prepare in one step from commercially available materials and afford good levels of asymmetric induction in the catalytic allylic substitution process of up to 81% ee. The stereochemical outcome is described in terms of steric and electronic factors.

引用

页码：2015 / 2018

页数：4

共 24 条

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