IDENTIFICATION OF THE REMAINS OF THE ROMANOV FAMILY BY DNA ANALYSIS

被引:391
作者
GILL, P
IVANOV, PL
KIMPTON, C
PIERCY, R
BENSON, N
TULLY, G
EVETT, I
HAGELBERG, E
SULLIVAN, K
机构
[1] CENT RES & SUPPORT ESTAB,FORENS SCI SERV,READING RG7 4PN,BERKS,ENGLAND
[2] ENGELHARDT MOLEC BIOL INST,MOSCOW 117984,RUSSIA
[3] UNIV CAMBRIDGE,DEPT BIOL ANTHROPOL,CAMBRIDGE CB2 3DZ,ENGLAND
关键词
D O I
10.1038/ng0294-130
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
Nine skeletons found in a shallow grave in Ekaterinburg, Russia, in July 1991, were tentatively identified by Russian forensic authorities as the remains of the last Tsar, Tsarina, three of their five children, the Royal Physician and three servants. We have performed DNA based sex testing and short tandem repeat (STR) analysis and confirm that a family group was present in the grave. Analysis of mitochondrial (mt) DNA reveals an exact sequence match between the putative Tsarina and the three children with a living maternal relative. Amplified mtDNA extracted from the remains of the putative Tsar has been cloned to demonstrate heteroplasmy at a single base within the mtDNA control region. One of these sequences matches two living maternal relatives of the Tsar. We conclude that the DNA evidence supports the hypothesis that the remains are those of the Romanov family.
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页码:130 / 135
页数:6
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