AN IMPROVED POST-SYNTHETIC SUBSTITUTION APPROACH FOR SYNTHESIS OF OLIGODEOXYNUCLEOTIDES CONTAINING LABILE 4-SUBSTITUTED THYMINES

被引：7

作者：

ZHENG, QG

XU, YZ

SWANN, PF

机构：

[1] Department of Biochemistry and Molecular Biology, Cancer Research Campaign, Nitrosamine-Induced Cancer Research Group, University College London, London WC1E 6BT, Gower Street

来源：

NUCLEOSIDES & NUCLEOTIDES | 1995年 / 14卷 / 3-5期

关键词：

D O I：

10.1080/15257779508012506

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A simple procedure is described for the preparation of a versatile oligodeoxynucleotide which contains 4-phenylthiothymidine. This versatile oligomer has been successfully used for synthesis of oligonucleotides containing labile 5-methyl-N-4,N-4-ethanocytosine (7) or 4-azido-5-methyl-2-pyrimidinone-1-beta-(2'-deoxyriboside) (8).

引用

页码：939 / 942

页数：4

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