HYPOTHESIS - HELICOBACTER-PYLORI, UREASE, MUCUS, AND GASTRIC-ULCER

被引:67
作者
SIDEBOTHAM, RL [1 ]
BARON, JH [1 ]
机构
[1] HAMMERSMITH HOSP,ROYAL POSTGRAD MED SCH,LONDON W12 0NN,ENGLAND
关键词
D O I
10.1016/0140-6736(90)90279-E
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Ammonia, released in the gastric mucosa by the action of Helicobacter pylori urease on transuded plasma urea, curtails the biosynthesis of mucus and/or causes the mucus to be disassembled at the mucosal surface. These changes facilitate colonisation by H pylori and may promote gastric ulcer formation. © 1990.
引用
收藏
页码:193 / 195
页数:3
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