BASE-LINE SEROEPIDEMIOLOGY OF HEPATITIS-A VIRUS-INFECTION AMONG CHILDREN AND TEENAGERS IN ITALY

被引：35

作者：

STROFFOLINI, T ^{[1
]}

CHIARAMONTE, M ^{[1
]}

FRANCO, E ^{[1
]}

RAPICETTA, M ^{[1
]}

DEMATTIA, D ^{[1
]}

MURA, I ^{[1
]}

TRIVELLO, R ^{[1
]}

GIAMMANCO, A ^{[1
]}

RIGO, G ^{[1
]}

SCARPA, B ^{[1
]}

机构：

[1] IST SUPER SANITA,VIROL LAB,I-00161 ROME,ITALY

来源：

INFECTION | 1991年 / 19卷 / 02期

关键词：

D O I：

10.1007/BF01645576

中图分类号：

R51 [传染病];

学科分类号：

100401 ;

摘要：

During the period from May 1987 through November 1989, the prevalence of antibodies to hepatitis A virus infection (anti-HAV) was assayed by the ELISA method in the serum samples of 5,507 (54% males, 46% females) apparently healthy subjects three to 19 years old in Italy. Subjects were selected by a systematic cluster sampling in five different geographical areas of Italy. The overall prevalence of anti-HAV was 9.5%; it increased from 2.3% among children three to five-years-old to 16.3% in teenagers 17 to 19 years old (p < 0.001). A slight preponderance of females was observed (10% versus 9.1%), but the difference was not statistically significant. The prevalence was significantly higher in Southern Italy than in Northern Italy (27.4% versus 4.8%; p < 0.01). The prevalence of anti-HAV was inversely related to the father's years of schooling (O.R.3.3; 95% C.I. = 2.5 - 4.2) and positively related to the family size (O.R. 2.4; 95% C.I. = 1.9 - 3.1). These findings indicate that, today, exposure to HAV infection at a young age in Italy is very low. However, sociodemographic factors are still important determinants in the spread of this infection.

引用

页码：97 / 100

页数：4

共 10 条

[1]

Abramson JH, 1983, SURVEY METHODS COMMU, P25

[2]

Ayoola E, 1988, VIRAL HEPATITIS LIVE, P161

[3] CHANGING SEROEPIDEMIOLOGY OF HEPATITIS-A VIRUS-INFECTION IN TAIWAN [J].