AN ACCURATE METHOD FOR DETERMINATION OF RECEPTOR LIGAND AND ENZYME-INHIBITOR DISSOCIATION-CONSTANTS FROM DISPLACEMENT CURVES

被引：78

作者：

HOROVITZ, A

LEVITZKI, A

机构：

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 1987年 / 84卷 / 19期

关键词：

D O I：

10.1073/pnas.84.19.6654

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：6654 / 6658

页数：5

共 13 条

[1] COMPETITIVE INHIBITION - NEW AND GENERAL LINEAR RELATIONS [J].

BESTBELPOMME, M ;

DESSEN, P .

BIOCHIMIE, 1973, 55 (01) :11-16

[2] QUANTITATIVE ASPECTS OF HORMONE-RECEPTOR INTERACTIONS OF HIGH AFFINITY - EFFECT OF RECEPTOR CONCENTRATION AND MEASUREMENT OF DISSOCIATION-CONSTANTS OF LABELED AND UNLABELED HORMONES [J].

CHANG, KJ ;

JACOBS, S ;

CUATRECASAS, P .

BIOCHIMICA ET BIOPHYSICA ACTA, 1975, 406 (02) :294-303

[3]

CHENG Y, 1973, BIOCHEM PHARMACOL, V22, P3099

[4]

DELEAN A, 1982, MOL PHARMACOL, V21, P5

[5] GRAPHICAL DETERMINATION OF KM AND KI [J].

DIXON, M .

BIOCHEMICAL JOURNAL, 1972, 129 (01) :197-&

[6] THE DETERMINATION OF ENZYME INHIBITOR CONSTANTS [J].

DIXON, M .

BIOCHEMICAL JOURNAL, 1953, 55 (01) :170-171

[7] PANCREATIC TRYPSIN INHIBITOR .2. REACTION WITH TRYPSIN [J].

GREEN, NM ;

WORK, E .

BIOCHEMICAL JOURNAL, 1953, 54 (02) :347-352

[8] STEADY-STATE ENZYME-KINETICS WITH HIGH-AFFINITY SUBSTRATES OR INHIBITORS - STATISTICAL TREATMENT OF DOSE-RESPONSE CURVES [J].

HENDERSON, PJ .

BIOCHEMICAL JOURNAL, 1973, 135 (01) :101-107

[9] LINEAR EQUATION THAT DESCRIBES STEADY-STATE KINETICS OF ENZYMES AND SUBCELLULAR PARTICLES INTERACTING WITH TIGHTLY BOUND INHIBITORS [J].

HENDERSON, PJ .

BIOCHEMICAL JOURNAL, 1972, 127 (02) :321-+

[10] LIGAND SPECIFICITY AND CHARACTERISTICS OF BETA-ADRENERGIC-RECEPTOR IN TURKEY ERYTHROCYTE PLASMA-MEMBRANES [J].

LEVITZKI, A ;

SEVILIA, N ;

ATLAS, D ;

STEER, ML .

JOURNAL OF MOLECULAR BIOLOGY, 1975, 97 (01) :35-46

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