HUMAN DRUG-METABOLISM INVITRO

被引：37

作者：

BEAUNE, PH ^{[1
]}

GUENGERICH, FP ^{[1
]}

机构：

[1] VANDERBILT UNIV,MED CTR,SCH MED,DEPT BIOCHEM,CTR MOLEC TOXICOL,NASHVILLE,TN 37232

来源：

PHARMACOLOGY & THERAPEUTICS | 1988年 / 37卷 / 02期

关键词：

D O I：

10.1016/0163-7258(88)90025-3

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：193 / 211

页数：19

共 159 条

[1] METHODS FOR DETECTING CARCINOGENS AND MUTAGENS WITH SALMONELLA-MAMMALIAN-MICROSOME MUTAGENICITY TEST [J].

AMES, BN ;

MCCANN, J ;

YAMASAKI, E .

MUTATION RESEARCH, 1975, 31 (06) :347-363

[2] HUMAN ANTI-ENDOPLASMIC RETICULUM AUTOANTIBODIES APPEARING IN A DRUG-INDUCED HEPATITIS ARE DIRECTED AGAINST A HUMAN-LIVER CYTOCHROME-P-450 THAT HYDROXYLATES THE DRUG [J].

BEAUNE, P ;

DANSETTE, PM ;

MANSUY, D ;

KIFFEL, L ;

FINCK, M ;

AMAR, C ;

LEROUX, JP ;

HOMBERG, JC .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1987, 84 (02) :551-555

[3] THE SALMONELLA MAMMALIAN MICROSOME MUTAGENICITY TEST - COMPARISON OF HUMAN AND RAT LIVERS AS ACTIVATING SYSTEMS [J].

BEAUNE, P ;

LEMESTRECORNET, R ;

KREMERS, P ;

ALBERT, A ;

GIELEN, J .

MUTATION RESEARCH, 1985, 156 (03) :139-146

[4] MONOCLONAL-ANTIBODIES AGAINST HUMAN-LIVER CYTOCHROME-P-450 [J].

BEAUNE, P ;

KREMERS, P ;

LETAWEGOUJON, F ;

GIELEN, JE .

BIOCHEMICAL PHARMACOLOGY, 1985, 34 (19) :3547-3552

[5] PURIFICATION OF A NEW CYTOCHROME-P-450 FROM HUMAN-LIVER MICROSOMES [J].

BEAUNE, P ;

FLINOIS, JP ;

KIFFEL, L ;

KREMERS, P ;

LEROUX, JP .

BIOCHIMICA ET BIOPHYSICA ACTA, 1985, 840 (03) :364-370

[6] ISOLATION AND SEQUENCE DETERMINATION OF A CDNA CLONE RELATED TO HUMAN CYTOCHROME-P-450 NIFEDIPINE OXIDASE [J].

BEAUNE, PH ;

UMBENHAUER, DR ;

BORK, RW ;

LLOYD, RS ;

GUENGERICH, FP .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1986, 83 (21) :8064-8068

[7]

BEAUNE PH, 1986, DRUG METAB DISPOS, V14, P437

[8] CULTURED HUMAN ADULT HEPATOCYTES - A NEW MODEL FOR DRUG-METABOLISM STUDIES [J].

BEGUE, JM ;

LEBIGOT, JF ;

GUGUENGUILLOUZO, C ;

KIECHEL, JR ;

GUILLOUZO, A .

BIOCHEMICAL PHARMACOLOGY, 1983, 32 (10) :1643-1646

[9] ACTION OF DRUGS ON BILIRUBIN METABOLISM IN MAN [J].

BILLING, BH ;

BLACK, M .

ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 1971, 179 (JUL6) :403-&

[10] METABOLISM OF 17 ALPHA-ETHYNYLESTRADIOL BY HUMAN LIVER-MICROSOMES INVITRO - AROMATIC HYDROXYLATION AND IRREVERSIBLE PROTEIN-BINDING OF METABOLITES [J].

BOLT, HM ;

KAPPUS, H ;

KASBOHRER, R .

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 1974, 39 (06) :1072-1080

← 1 2 3 4 5 6 7 8 9 10 →