INTERLEUKIN-6 IS THE MAJOR REGULATOR OF ACUTE PHASE PROTEIN-SYNTHESIS IN ADULT HUMAN HEPATOCYTES

被引：803

作者：

CASTELL, JV

GOMEZLECHON, MJ

DAVID, M

ANDUS, T

GEIGER, T

TRULLENQUE, R

FABRA, R

HEINRICH, PC

机构：

[1] UNIV FREIBURG,INST BIOCHEM,HERMANN HERDER STR 7,D-7800 FREIBURG,FED REP GER

[2] UNIV FREIBURG,MED KLIN,D-7800 FREIBURG,FED REP GER

[3] HOSP LA FE,INSALUD,CTR INVEST,E-46009 VALENCIA,SPAIN

[4] HOSP GEN VALENCIA,SERV CIRUGIA,E-46018 VALENCIA,SPAIN

来源：

FEBS LETTERS | 1989年 / 242卷 / 02期

关键词：

D O I：

10.1016/0014-5793(89)80476-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：237 / 239

页数：3

共 13 条

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[2] REGULATION OF SYNTHESIS AND SECRETION OF MAJOR RAT ACUTE-PHASE PROTEINS BY RECOMBINANT HUMAN INTERLEUKIN-6 (BSF-2/IL-6) IN HEPATOCYTE PRIMARY CULTURES [J].

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[3] RECOMBINANT HUMAN B-CELL STIMULATORY FACTOR-II (BSF-2/IFN-BETA2) REGULATES BETA-FIBRINOGEN AND ALBUMIN MESSENGER-RNA LEVELS IN FAO-9 CELLS [J].

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[4] RECOMBINANT HUMAN INTERLEUKIN-6 (IL-6/BSF-2/HSF) REGULATES THE SYNTHESIS OF ACUTE PHASE PROTEINS IN HUMAN HEPATOCYTES [J].

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HIRANO, T ;

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FEBS LETTERS, 1988, 232 (02) :347-350

[5] MONOCYTE-CONDITIONED MEDIUM, INTERLEUKIN-1, AND TUMOR-NECROSIS-FACTOR STIMULATE THE ACUTE PHASE RESPONSE IN HUMAN HEPATOMA-CELLS INVITRO [J].

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[6]

DINARELLO CA, 1984, NEW ENGL J MED, V311, P1413

[7] INTERFERON BETA-2/B-CELL STIMULATORY FACTOR TYPE-2 SHARES IDENTITY WITH MONOCYTE-DERIVED HEPATOCYTE-STIMULATING FACTOR AND REGULATES THE MAJOR ACUTE PHASE PROTEIN RESPONSE IN LIVER-CELLS [J].

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[8] COMPLEMENTARY-DNA FOR A NOVEL HUMAN INTERLEUKIN (BSF-2) THAT INDUCES LYMPHOCYTES-B TO PRODUCE IMMUNOGLOBULIN [J].

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[9] ABSENCE OF ANTIVIRAL ACTIVITY IN RECOMBINANT B-CELL STIMULATORY FACTOR-II (BSF-2) [J].

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[10] A CYTOKINE NETWORK IN HUMAN-DIPLOID FIBROBLASTS - INTERACTIONS OF BETA-INTERFERONS, TUMOR-NECROSIS-FACTOR, PLATELET-DERIVED GROWTH-FACTOR, AND INTERLEUKIN-1 [J].

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